8.23.21 Dariya Lizanets joins us as a new MS student We are happy to welcome new MS student Dariya, who joins us this semester after graduating from Rutgers University. She will be working with our microfluidic 3D cell culture systems to explore the effects of radiation on lung tissue. Welcome Dariya!
8.20.21 Another collaborative paper available Our group's collaborative work with the lab of Dr. Heidi Reesink (Cornell) has resulted in a new publication in Arthritis Research & Therapy! The paper focuses on HA and HC-HA in equine synovial fluid and our group contributed high-sensitivity nanopore size analyses to the effort. Congratulations to Felipe and the rest of the team!
8.18.21 New collaborative paper published A new paper has been published in collaboration with Drs. Steve Soper (Kansas), Sunggook Park (LSU), and others! Featured in ACS Sensors, it describes fabrication control over the dimensions of in-plane nanopores formed with manufacturable methods and materials. This is part of a larger research program emerging in our lab geared towards sequencing applications. Congrats to all authors!
7.1.21 Adam promoted to Associate Professor with tenure Adam's application for promotion and tenure was approved earlier in the year and officially kicks in today. The biggest outcome: we get to continue trying to do good science for the foreseeable future! Thank you to all of the students and postdocs (past and present) who have made our lab successful through their hard work and to all the colleagues around the world for their support of both the research we do and the people who do it.
6.14.21 Group presents at International Society for Hyaluronan Sciences Conference Our lab presented two talks at the 2021 virtual ISHAS conference. Dorothea detailed her recent work on isolating heavy chain HA in a talk that can be seen here and Felipe presented his project on optimizing nanopore analysis of HA, which can be seen here. Great job!
6.9.21 Congratulations to Nathan Hauser: Master of Science! Nathan has successfully defended his Master's thesis entitled "Development of Combined 3-Dimensional Tissue Culture and Microfluidics Systems for Use in the Study of Disease States and Their Treatments"! He will be sticking around Winston Salem for a while as he joins friend-of-the-lab Dr. Ellie Rahbar as a technician before planning out his next move. Contrats, Nathan!
6.1.21 Welcome Taylor Nolan! Taylor Nolan is joining us this summer as a NSF REU student. She is about to enter her final year at Old Dominion University and will be spending her time in our lab focusing on solid-state nanopores and their application to detecting nucleic acid sequence biomarkers. Welcome to the lab!
5.16.21 Congratulations to new alum Lucy Vaughn Lucy earned her BS this weekend as part of the inaugural graduating class of Wake Forest Engineering! She will now move on to AstraZeneca as a Development Engineering Associate. Congrats and thank you for all your contributions to the lab!
4.29.21 New paper in Nanomedicine: Nanotechnology, Biology and Medicine The group has a new paper accepted in Nanomedicine: Nanotechnology, Biology and Medicine detailing nanopore analysis of hydroxymethylcytosine (hmC) modifications in human genomic DNA! We report that the established decrease in hmC found in breast cancer DNA is associated with advanced stage disease rather than early. Congratulations to Osama and all authors!
4.29.21 New paper published today in ACS Nano Congratulations to Komal and all contributing authors on the publication of a manuscript in ACS Nano! The paper describes the implementation of our selective solid-state nanopore assay in the detection and quantification of sequence motifs in single-strand DNA and RNA genomes. We use HIV RNA as a model to demonstrate viral detection.
3.15.21 Hyaluronan services now available We are happy to announce that we are now offering hyaluronan services to the research community. This includes high-fidelity isolation from diverse biological matrices and molecular weight distribution analysis from as little as 10 ng of total glycan. We can also perform quantitation using an ELISA-like assay. See our new services page for more details!
1.26.21 Welcome to our newest lab member! A big welcome to Sara Abu Jalboush, the newest addition to our lab! Sara is in the Cancer Biology program and will be working on epigenetics applications of solid-state nanopore technology. Her expertise will bring a new perspective to the lab's work.